Kirin has filed a patent for a film coated tablet that aims to improve tablet slipperiness in the oral cavity and prevent delays in tablet disintegration. The tablet consists of a first film layer containing an inorganic salt, a second film layer containing a thickener, and a tablet coated with both layers. The inorganic salt reduces the viscosity of the thickener in the second film layer. GlobalData’s report on Kirin gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Kirin, Lactobacilli-based drug compositions was a key innovation area identified from patents. Kirin's grant share as of September 2023 was 27%. Grant share is based on the ratio of number of grants to total number of patents.

Film coated tablet with improved slipperiness and disintegration time

Source: United States Patent and Trademark Office (USPTO). Credit: Kirin Holdings Co Ltd

A recently filed patent (Publication Number: US20230263735A1) describes a film-coated tablet with specific compositions and properties. The tablet consists of a core tablet coated with two film layers.

The first film layer contains an inorganic salt, which is a water-soluble inorganic salt such as potassium phosphate, sodium hydrogen carbonate, or sodium chloride. The content of the inorganic salt in the first film layer is between 20 to 55% by mass.

The second film layer, which coats the outside of the first film layer, contains a thickener. The thickener can be sodium alginate or xanthan gum, and its content in the second film layer is between 20 to 40% by mass.

The patent also specifies the proportions of the film layers in relation to the uncoated tablet. The first film layer is 2 to 6 parts by mass per 100 parts by mass of the uncoated tablet, while the second film layer is 2 to 4 parts by mass per 100 parts by mass of the uncoated tablet.

Additionally, the patent claims that the inorganic salt in the first film layer reduces the viscosity of the thickener in the second film layer. This property is achieved by the specific combination of the inorganic salt and the thickener.

Furthermore, the patent describes an alternative embodiment where the first film layer also contains a water-soluble film base with a 2% by mass aqueous solution viscosity at 20°C of 100 mPa•s or less.

Overall, this patent presents a novel film-coated tablet formulation with specific compositions and proportions of inorganic salt and thickener in the film layers. The combination of these ingredients and their specific properties provide unique benefits, such as reduced viscosity and improved coating performance. This innovation has the potential to enhance the effectiveness and stability of film-coated tablets in various applications.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.