Ajinomoto has patented a method for producing RNA using a modified coryneform bacterium with reduced ribonuclease III activity. The process involves culturing the bacterium in a medium to accumulate the RNA and then collecting it from the cells. GlobalData’s report on Ajinomoto gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Ajinomoto, Cancer treatment biomarkers was a key innovation area identified from patents. Ajinomoto's grant share as of February 2024 was 45%. Grant share is based on the ratio of number of grants to total number of patents.
Method for producing rna using modified coryneform bacterium
A recently granted patent (Publication Number: US11884951B2) discloses a method for producing objective RNA using a coryneform bacterium that has been genetically modified to reduce the activity of ribonuclease III. The method involves culturing the bacterium in a medium to express and accumulate the objective RNA in the cells, followed by collecting the RNA. The ribonuclease III protein in the bacterium is selected from specific sequences or variants with reduced activity compared to non-modified strains.
Furthermore, the patent claims specify details such as the number of copies of the expression unit in the bacterium, the presence of a vector containing the expression unit, and the specific promoter sequences used in the method. The bacterium mentioned in the claims belongs to the genus Corynebacterium, with a specific reference to Corynebacterium glutamicum. The method outlined in the patent aims to provide a reliable and efficient way to produce objective RNA using genetically modified coryneform bacteria, potentially opening up new possibilities in RNA production technology.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
