Firmenich International has filed a patent for biocatalytic methods of producing terpene degradation products, which can be used as starting material for perfumery ingredients. The patent describes novel enzymes and pathways for the controlled conversion and degradation of terpene substrates, allowing for the biochemical synthesis of valuable terpene-derived compounds. Recombinant host organisms carrying the necessary genetic information for enzyme expression are also mentioned. GlobalData’s report on Firmenich International gives a 360-degree view of the company including its patenting strategy.
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According to GlobalData’s company profile on Firmenich International, nanoemulsion cosmetics was a key innovation area identified from patents.
Biocatalytic methods for producing terpene degradation products
A recently filed patent (Publication Number: US20230183761A1) describes a biocatalytic method for preparing compounds of the general formula IV, specifically labdane-type terpenes. The method involves the application of a terpene precursor of formula V, which can have various substituents and functional groups. The method also utilizes specific polypeptides with enal-cleaving activity, which are selected from different protein families or have specific sequence motifs/domains. These polypeptides are responsible for degrading the terpene precursor and facilitating the formation of the desired compound.
The patent also discloses additional steps for processing the compound of formula IV to obtain derivatives using chemical or biocatalytic synthesis or a combination of both. These derivatives can have various functional groups and can be isolated if desired. Furthermore, the patent describes methods for preparing epoxy-tetranorlabdane compounds and diepoxy-dinorlabdane compounds, which involve the conversion of specific precursors using chemical and/or biochemical conversion steps.
Overall, this patent presents a biocatalytic method for preparing labdane-type terpenes and their derivatives, providing a potential approach for the efficient production of these compounds. The use of specific polypeptides with enal-cleaving activity and the ability to process the compounds to obtain derivatives offer versatility and potential applications in various industries, including pharmaceuticals, fragrances, and flavors.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
