Most observational epidemiologic studies have shown a slight increase in the risk of breast cancer for women who consume alcohol; the degree of increase is usually small for light-to-moderate drinkers (between 5% and 15% increase for consumers of no more than one drink/day), but the risk may be higher for women consuming greater amounts of alcohol. There are a number of factors that affect this relationship, however, including the type of study (cohort or case-control), the pattern of drinking (regular versus binge), the type of beverage consumed, folate intake, use of hormone replacement therapy, as well as genetic factors.
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