Kikkoman patented a novel method to quantify ethanolamine phosphate, a biomarker for depression. The method involves adding oxidoreductase to a sample, allowing it to act on ethanolamine phosphate, and using a mediator or hydrogen peroxide to determine the concentration. GlobalData’s report on Kikkoman gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Kikkoman, Nanoemulsion cosmetics was a key innovation area identified from patents. Kikkoman's grant share as of February 2024 was 36%. Grant share is based on the ratio of number of grants to total number of patents.

Quantification method for ethanolamine phosphate using oxidoreductase

Source: United States Patent and Trademark Office (USPTO). Credit: Kikkoman Corp

The granted patent (Publication Number: US11879149B2) discloses a quantitation method for ethanolamine phosphate using an oxidoreductase enzyme. The method involves adding the oxidoreductase to a sample containing ethanolamine phosphate, allowing it to act on the substrate, and then determining the concentration of ethanolamine phosphate in the sample. The oxidoreductase used in the method belongs to EC NO: 1.4 or EC NO: 1.5, with specific examples including primary amine dehydrogenase, monoamine dehydrogenase, and ethanolamine dehydrogenase among others.

Furthermore, the method may also include reducing a mediator by adding the oxidoreductase, and then reacting the reduced mediator with a reagent to determine the concentration of ethanolamine phosphate. The oxidoreductase can be an oxidase, with hydrogen peroxide produced by the oxidase reacting with a reagent to determine the concentration of ethanolamine phosphate. The patent also specifies that the oxidoreductase can be selected from a group of enzymes including tyramine oxidase, histamine oxidase, and taurine oxidase, among others. The method provides a novel approach to quantifying ethanolamine phosphate levels in samples, offering potential applications in various fields such as biochemistry and pharmaceutical research.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.