According to GlobalData’s company profile on Danone, Lactobacilli-based drug compositions was a key innovation area identified from patents. Danone's grant share as of September 2023 was 52%. Grant share is based on the ratio of number of grants to total number of patents.

The patent filed is for a method of improving blood plasma uridine levels

A recently filed patent (Publication Number: US20230293567A1) describes a method for therapeutically improving and prolonging blood plasma uridine levels and tissue availability of uridine, as well as treating disorders associated with impaired uridine availability. The method involves orally administering a composition to a human in need, which includes sodium in a soluble form and uridine or sodium-free uridine derivatives. The molar ratio of sodium to uridine in the composition is more than 1:1, and in some embodiments, it is more than 1.5:1 or more than 2:1.

The patent claims that the method is particularly useful for individuals at increased risk of or suffering from neurological disorders, diabetes, insulin resistance, stroke, endothelial damage, or fatty liver. Specifically, it may benefit those with memory and cognitive disorders such as Age Associated Memory Impairment (AAMI), Alzheimer's Disease, Parkinson's disease, Pick's disease, dementia (including vascular dementia, frontotemporal dementia, semantic dementia, or dementia with Lewy bodies), and Mild Cognitive Impairment (MCI).

The patent suggests that the uridine can be provided in an amount of about 30-1000 mg per day, with a preferred range of 200-800 mg per day. Additionally, the method may involve administering docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), and docosapentaenoic acid (DPA), or esters thereof. The composition may also include choline or its salts or esters, as well as vitamin B6, B12, or B9.

Another aspect of the patent describes a nutritional composition that includes uridine and sodium in a soluble form, with a molar ratio of sodium to uridine of more than 1:1. This composition may also contain DHA, EPA, DPA, choline or its salts or esters, and vitamin B6, B12, or B9. The total amount of uridine in the composition is about 30-1000 mg per ml, and a preferred range is 200-800 mg per 100 ml.

In summary, the patent claims a method and nutritional composition for improving uridine levels and treating disorders associated with impaired uridine availability. The method involves orally administering a composition containing sodium and uridine or sodium-free uridine derivatives, while the nutritional composition includes additional components such as DHA, EPA, DPA, choline, and vitamin B. These approaches may be beneficial for individuals with neurological disorders, diabetes, stroke, or memory and cognitive disorders.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.