CJ has been granted a patent for a modified microorganism from the genus Corynebacterium that produces L-leucine. The microorganism contains a modified polypeptide with specific amino acid substitutions and enhanced promoter for increased expression of the polynucleotide. GlobalData’s report on CJ gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on CJ, NSAID cancer drugs was a key innovation area identified from patents. CJ's grant share as of February 2024 was 46%. Grant share is based on the ratio of number of grants to total number of patents.
A recently granted patent (Publication Number: US11905539B2) discloses a modified microorganism from the genus Corynebacterium designed for the production of L-leucine. The modified microorganism contains a modified polypeptide with specific amino acid substitutions and a promoter that enhances the expression of the polynucleotide encoding the modified polypeptide. Derived from Corynebacterium glutamicum, this engineered microorganism exhibits resistance to norleucine or L-leucine, crucial for efficient L-leucine production.
The patent also outlines a method for producing L-leucine using the modified microorganism. The process involves culturing the engineered microorganism in a suitable medium to produce L-leucine and then recovering the L-leucine from the cultured microorganism or medium. By utilizing a non-native promoter, such as the PCJ7 promoter, the method aims to enhance the expression of the polynucleotide encoding the modified polypeptide, thereby increasing the productivity of L-leucine. Additionally, the patent describes the transformation of the modified microorganism with a vector containing the necessary genetic elements to further enhance L-leucine productivity, emphasizing the use of non-native promoters like PCJ7 for this purpose.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
