Church & Dwight. has filed a patent for compositions and methods to convert oleuropein to hydroxytyrosol using Lactobacillus pentosus strain OL79 or active variants. The invention aims to increase hydroxytyrosol levels for various health benefits, including antioxidant and anti-inflammatory activity, cardiovascular protection, and therapeutic effects on oxidative stress-related diseases. The patent also includes a claim for a bacterial strain composition containing Lactobacillus pentosus strain OL79, oleuropein, and a pharmaceutically acceptable carrier. GlobalData’s report on Church & Dwight gives a 360-degree view of the company including its patenting strategy. Buy the report here.
Smarter leaders trust GlobalData
According to GlobalData’s company profile on Church & Dwight, Nanoparticle drug conjugates was a key innovation area identified from patents. Church & Dwight's grant share as of September 2023 was 61%. Grant share is based on the ratio of number of grants to total number of patents.
The patent is filed for a composition and method for converting oleuropein to hydroxytyrosol using a specific bacterial strain
A recently filed patent (Publication Number: US20230256039A1) describes a bacterial strain composition that includes a bacterial cell of Lactobacillus pentosus strain OL79 or an active variant thereof. The composition contains the bacterial cell at a concentration ranging from about 106 CFU/gram to about 1010 CFU/gram or from about 106 CFU/ml to about 1010 CFU/ml. Additionally, the composition may include oleuropein and a pharmaceutically acceptable carrier if it is intended for pharmaceutical use.
The patent claims that the bacterial strain composition can be combined with plants, plant parts, or extracts containing oleuropein. Specifically, the composition can include olive plants, olive plant parts, or extracts thereof. When administered in an effective amount, the composition is said to increase the conversion of oleuropein to hydroxytyrosol, reduce oxidative stress, inflammation, and platelet aggregation, and potentially treat cardiovascular disease, metabolic disease, inflammatory disease, neurodegenerative disease, or cancer in subjects.
The method described in the patent involves contacting oleuropein with the bacterial strain composition to increase hydroxytyrosol production. This method can also involve contacting plants, plant parts, or extracts containing oleuropein with the bacterial strain composition, with olive plants, olive plant parts, or extracts being specifically mentioned. Another method described in the patent involves administering the bacterial strain composition to a subject to increase the amount of hydroxytyrosol in the subject. In this method, the subject may also be administered oleuropein and plants, plant parts, or extracts containing oleuropein, with olive plants, olive plant parts, or extracts being mentioned again.
The patent also claims that the bacterial strain composition can be used to reduce or prevent oxidative stress, inflammation, and platelet aggregation in subjects. This method can involve treating diseases or conditions associated with oxidative stress, inflammation, or platelet aggregation, such as cardiovascular disease, metabolic disease, inflammatory disease, neurodegenerative disease, or cancer.
Overall, the patent describes a bacterial strain composition containing Lactobacillus pentosus strain OL79 or an active variant thereof, which can be combined with oleuropein and potentially used to increase hydroxytyrosol production, reduce oxidative stress, inflammation, and platelet aggregation, and treat various diseases and conditions. The composition can be administered orally or dermally and may be formulated as a capsule, gel, paste, cream, ointment, tablet, powder, or liquid.
To know more about GlobalData’s detailed insights on Church & Dwight, buy the report here.
Data Insights
From
The gold standard of business intelligence.
Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.
GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.
