Morinaga Milk Industry. has filed a patent for a prebiotic composition that efficiently promotes the growth of butyrate-producing bacteria. The composition includes an oligosaccharide made of specific acids and can be produced by acting an alginate lyase on alginic acid. GlobalData’s report on Morinaga Milk Industry gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Morinaga Milk Industry, Lactobacilli-based drug compositions was a key innovation area identified from patents. Morinaga Milk Industry's grant share as of January 2024 was 30%. Grant share is based on the ratio of number of grants to total number of patents.
Prebiotic composition for butyrate-producing bacterium using specific oligosaccharide
The patent application (Publication Number: US20240016825A1) discloses a prebiotic composition designed to promote the growth of a butyrate-producing bacterium. The composition includes an oligosaccharide containing ß-D-mannuronic acid and/or a-L-guluronic acid, with an unsaturated form of these acids at the non-reducing end. Specifically, the unsaturated form features a double bond between carbon atoms at positions 4 and 5, and the oligosaccharide has a polymerization degree of 2 to 10.
Moreover, the composition is effective for various health benefits, including intestinal regulation, immunomodulation, reduction in oxidative stress, prevention or improvement of diarrhea, inflammatory bowel disease, and large intestine cancer. The composition can be consumed as food or drink, or used as a pharmaceutical product. Additionally, the patent application outlines methods for producing the prebiotic composition using alginate lyase to act on alginic acid, forming a degradation product that can be formulated as a prebiotic composition. The method also involves collecting oligosaccharides with a polymerization degree of 2 to 3, further enhancing the growth of butyrate-producing bacteria, particularly Faecalibacterium, such as Faecalibacterium prausnitzii.
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