111 results in the archive - showing page 1 of 4

Can alcohol consumption slow the onset of dementia? - International Scientific Forum on Alcohol Research Critique 233 11 Nov 2019

Column: Critiques from the International Scientific Forum on Alcohol Research

The latest study to go under The ISFAR's microscope was designed to assess the association between alcohol consumption and dementia and the roles of mild cognitive impairment (MCI) and apolipoproteinEe4 (APOEE4) genotype in modifying this association.


Does moderate alcohol consumption in later life reduce the risk of mortality? - International Scientific Forum on Alcohol Research Critique 232 4 Sep 2019

Column: Critiques from the International Scientific Forum on Alcohol Research

There are well-known problems inherent in most observational studies of alcohol and health. As well as having to rely on self-reporting of intake, these include single-time point consumption assessments, inadequate confounder adjustments, accounting for reverse causation, selection bias, short follow-up, residual confounding and lacking information on chronic health conditions that may mediate the association between alcohol consumption and mortality.


What effect does alcohol consumption have on obesity? - International Scientific Forum on Alcohol Research Critique 231 21 Aug 2019

Column: Critiques from the International Scientific Forum on Alcohol Research

While alcoholic beverages contain calories that are absorbed, the association between alcohol intake and body weight and obesity is unclear. Limited clinical trials have not confirmed a positive association between alcohol intake and weight, while some epidemiologic studies, including prospective cohort studies, show that regular moderate drinkers are less likely to be obese than abstainers.


What effect do beverages have on developing diabetes? - International Scientific Forum on Alcohol Research Critique 230 20 Aug 2019

Column: Critiques from the International Scientific Forum on Alcohol Research

Of all lifestyle factors that relate to health and disease, probably the most difficult ones to evaluate are dietary factors, including foods, nutrients and beverages.


How alcohol can affect the development of colorectal cancer - International Scientific Forum on Alcohol Research Critique 229 11 Jul 2019

Column: Critiques from the International Scientific Forum on Alcohol Research

While heavy alcohol consumption is recognised as a contributor to the development of colorectal cancer (CRC), an increasing number of studies suggest that moderate alcohol consumption may not have an adverse effect on the risk of CRC, or even decrease the risk.


Could alcohol consumption affect the onset of pulmonary disease? - International Scientific Forum on Alcohol Research Critique 227 29 May 2019

Column: Critiques from the International Scientific Forum on Alcohol Research

Chronic obstructive pulmonary disease (COPD) is a major health problem and cause of death throughout the world. While cigarette smoking is known to be the most important risk factor, there is limited data available on the relation of alcohol consumption to the condition.


How red wine can reduce risk of lethal prostate cancer - International Scientific Forum on Alcohol Research Critique 226 16 May 2019

Column: Critiques from the International Scientific Forum on Alcohol Research

In an analysis from the Health Professionals Follow-up Study, investigators evaluated the relation of alcohol consumption in their over 45,000 study participants to the development of lethal prostate cancer. They related alcohol first to the overall risk of prostate cancer among all subjects, then focused on the 5,182 men who developed non-metastatic prostate cancer to judge their risk of developing lethal prostate cancer or mortality.


Can consuming alcohol reduce risk of chronic kidney disease? - International Scientific Forum on Alcohol Research Critique 225 8 Apr 2019

Column: Critiques from the International Scientific Forum on Alcohol Research

While many studies have found that moderate consumers of alcohol tend to be at a lower risk of developing chronic kidney disease (CKD), potential mechanisms for such an effect are unclear. A recent large prospective, population-based, multi-cultural study provides important additional data on the effects of alcohol intake on the initial diagnosis of CKD over many years.


Could consuming alcohol help with diabetes? - International Scientific Forum on Alcohol Research Critique 224 12 Mar 2019

Column: Critiques from the International Scientific Forum on Alcohol Research

Diabetes mellitus is an increasingly-common condition throughout the world, related closely to increases in obesity and ageing of populations. Scientific data from well-conducted cohort studies have demonstrated for decades that moderate consumers of alcohol tend to have a considerably lower risk of developing diabetes in the first place. Meanwhile, diabetics who consume moderate amounts of alcohol are, in comparison with abstainers, shown to be at much lower risk of developing cardiovascular disease.


Does alcohol consumption accelerate the chances of developing coronary heart disease? - International Scientific Forum on Alcohol Research Critique 222 21 Dec 2018

Column: Critiques from the International Scientific Forum on Alcohol Research

In an attempt to judge the effects of alcohol on the risk of coronary heart disease (CHD), a recent report carried out analyses using a sample of subjects from the National Epidemiologic Survey on Alcohol & Related Conditions III (NESARC-III). The authors based their exposure to current alcohol use on a single assessment at baseline of self-reported consumption during the past year, when the subjects were an average of 38.9 years of age.


Which alcohol category is better for avoiding stomach cancer? - International Scientific Forum on Alcohol Research Critique 221 20 Nov 2018

Column: Critiques from the International Scientific Forum on Alcohol Research

There have been conflicting results from studies of the association between alcohol intake and the risk of gastric cancer. Some of the differences among studies have related to mixing subjects from Western countries with those from Asia, where dietary patterns, lifestyle factors, drinking patterns and types of alcohol consumed differ from those among Western populations.


Why there's more to dying than just drinking - International Scientific Forum on Alcohol Research Critique 220 16 Oct 2018

Column: Critiques from the International Scientific Forum on Alcohol Research

For reasons unclear, the authors of a recent study into alcohol consumption and mortality combined results from two, very different studies; one from the Veterans’ Health Administration, based on outpatient clinical medical records, and the other from a national survey in the US [The National Health Interview Survey (NHIS)]. Unfortunately, the VA data did not adjust for tobacco use or other important lifestyle habits, and is not useful in judging the effects of alcohol consumption on mortality.


Can alcohol consumption guidelines be drawn up on a global basis? - International Scientific Forum on Alcohol Research Critique 219 4 Sep 2018

Column: Critiques from the International Scientific Forum on Alcohol Research

Investigators working with data from the Global Burden of Diseases, Injuries & Risk Factors Study 2016 have combined data from 195 locations around the world, from 1990 to 2016, for both sexes and for five-year age groups between the ages of 15 years and 95 years and older.


How will your alcohol intake affect the likelihood of dementia in later life? - International Scientific Forum on Alcohol Research Critique 218 22 Aug 2018

Column: Critiques from the International Scientific Forum on Alcohol Research

While there is general agreement that the moderate intake of alcohol is associated with a significantly-lower risk of cardiovascular disease, there is less data on the relation of moderate alcohol consumption to dementia. However, the vast majority of well-done prospective studies indicate that, in comparison with non-drinkers, moderate, non-binge-drinking older adults have lower risk of Alzheimer Disease and other types of dementia.


The more you drink, the greater your risk of cancer - International Scientific Forum on Alcohol Research Critique 217 11 Jul 2018

Column: Critiques from the International Scientific Forum on Alcohol Research

Scientific studies have shown consistently that the consumption of small amounts of alcohol on a regular basis is associated with a lower risk of total mortality, while consumption of large amounts is associated with an increased risk of certain cancers and mortality.


How best to fight the 'diseases of ageing' - International Scientific Forum on Alcohol Research Critique 216 10 Jul 2018

Column: Critiques from the International Scientific Forum on Alcohol Research

It has long been known that a number of lifestyle factors – such as not smoking, being physically active, avoiding obesity – decrease the risk of many of the 'diseases of ageing', especially cardiovascular disease and cancer.


Female? Smoker? What you should know about alcohol consumption - International Scientific Forum on Alcohol Research Critique 215 14 May 2018

Column: Critiques from the International Scientific Forum on Alcohol Research

While essentially all epidemiologic studies have shown adverse health effects of cigarette smoking and beneficial effects of moderate alcohol consumption, a recent study in this area that followed a cohort of elderly women into very old age proved interesting reading.


Should recommended alcohol consumption limits be reduced? - International Scientific Forum on Alcohol Research Critique 214 23 Apr 2018

Column: Critiques from the International Scientific Forum on Alcohol Research

Using individual-participant data from a number of large studies, predominantly from the UK and other European countries, the authors of a recent study have estimated the association between the reported level of alcohol intake among drinkers with cardiovascular outcomes and mortality.


What effect does alcohol have on middle-aged and elderly women? - International Scientific Forum on Alcohol Research Critique 213 28 Mar 2018

Column: Critiques from the International Scientific Forum on Alcohol Research

The ISFAR has been studying recently-released research that looks at the effect alcohol has on cardiovascular disease and mortality among a very large number of middle-aged or elderly women.


How much of a part does the alcohol play in wine's health effects? - International Scientific Forum on Alcohol Research Critique 212 15 Mar 2018

Column: Critiques from the International Scientific Forum on Alcohol Research

While epidemiologists have long noted that wine consumers tend to have better health outcomes than consumers of other alcoholic beverages, it has always been of concern that we were comparing drinkers, and not the drink itself.


Could alcohol be damaging to your DNA? - International Scientific Forum on Alcohol Research Critique 211 23 Jan 2018

Column: Critiques from the International Scientific Forum on Alcohol Research

The latest research to go under The ISFAR's microscope concerns an extensive basic scientific experiment in mice. The authors of the paper describe the features and mutational landscape of DNA damage caused by acetaldehyde, an endogenous and alcohol-derived metabolite.


Which alcohol category carries a lower risk of gastric cancer? - International Scientific Forum on Alcohol Research Critique 210 9 Jan 2018

Column: Critiques from the International Scientific Forum on Alcohol Research

While heavy alcohol intake has regularly been found to increase the risk of upper aero-digestive tract cancers (mouth, tongue, pharynx, larynx, etc), results are less clear for gastric cancer.


Does alcohol make you fat? - International Scientific Forum on Alcohol Research Critique 209 14 Dec 2017

Column: Critiques from the International Scientific Forum on Alcohol Research

The public, and scientists, have long been concerned about the relation between alcohol consumption and weight gain, as all alcoholic beverages contain calories. However, most epidemiologic studies do not find that light or moderate drinkers weigh more than their abstaining peers, and some even show lower weight among moderate drinkers than among abstainers.


The long-running battle to promote moderate drinking goes on - International Scientific Forum on Alcohol Research Critique 208 20 Nov 2017

Column: Critiques from the International Scientific Forum on Alcohol Research

A recently-released publication from the American Society of Clinical Oncology attempted to describe the relation between alcohol consumption and cancer, including the effects on the risk of developing cancer and effects among subjects currently being treated for cancer. It came to the conclusion that there is a need for the public to be warned about the use of alcohol because of its effects on cancer, and describes numerous approaches for decreasing alcohol use in the population.


Is there a 'right' amount of alcohol to drink when pregnant? - International Scientific Forum on Alcohol Research Critique 207 6 Nov 2017

Column: Critiques from the International Scientific Forum on Alcohol Research

There is no question that high levels of alcohol consumption during pregnancy can lead to severe adverse effects on the foetus, with the most serious condition known as fetal alcohol syndrome (FAS). Many studies have also related alcohol intake during pregnancy with premature birth, low birth weight, and the infant being small for gestational age (SGA). Data on the effects of occasional or light drinking are not as clear, but most studies have not detected adverse effects.


Why cultural differences are vital in gauging alcohol consumers' health - International Scientific Forum on Alcohol Research Critique 206 4 Oct 2017

Column: Critiques from the International Scientific Forum on Alcohol Research

It has been clearly shown that similar amounts of alcohol tend to have different health effects - both beneficial and adverse - in different cultures. Greater health benefits from moderate alcohol intake have been shown, for example, in southern European countries, where wine with meals is common, than in more northern European countries, where beer and spirits are more likely to be consumed and usually not with food.


How much alcohol will kill you, and when? - International Scientific Forum on Alcohol Research Critique 205 5 Sep 2017

Column: Critiques from the International Scientific Forum on Alcohol Research

The most usual finding in longitudinal cohort studies has been that light-to-moderate consumers of alcohol tend to be at lower risk for total mortality, and show greater longevity of life, even when other lifestyle/demographic factors known to affect longevity are adjusted for in the analysis. A recent analysis is important as it presents data on the relation of alcohol intake to total mortality as well as to specific mortality from cardiovascular disease (CVD) and cancer for a very large number of subjects in the US.


How much should you drink to help you live longer? - International Scientific Forum on Alcohol Research Critique 204 22 Aug 2017

Column: Critiques from the International Scientific Forum on Alcohol Research

A number of studies have shown that the risk of cognitive impairment appears to be reduced among elderly subjects who consume moderate amounts of alcohol; most studies indicate that both light and moderate drinking are associated with a lower risk of dementia, but heavy drinking is often shown to be associated with higher cognitive risk for dementia and cognitive impairment.


Why moderate drinking affects elderly consumers less than no drinking - International Scientific Forum on Alcohol Research Critique 203 8 Aug 2017

Column: Critiques from the International Scientific Forum on Alcohol Research

Falls are common among the elderly, and markedly increase the subsequent risk of morbidity and mortality. A recent study examined the association between certain patterns of alcohol consumption, including the Mediterranean drinking pattern (MDP), and the risk of falls in more than 2,000 elderly subjects over 3.3 years. At the end of follow up, 21.4% of subjects reported at least one fall in the previous year.


How important is folate intake for reducing breast cancer risk from alcohol consumption? - International Scientific Forum on Alcohol Research Critique 202 18 Jul 2017

Column: Critiques from the International Scientific Forum on Alcohol Research

The strongest factor associated with the risk of a woman developing breast cancer appears to be a positive family history of such a diagnosis in a sibling or mother. Among environmental factors, almost all studies have shown that alcohol consumption relates to increased risk; a slight increase is often seen even among women who report only light drinking - an average of less than one drink per day, for example.

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