The most usual finding in longitudinal cohort studies has been that light-to-moderate consumers of alcohol tend to be at lower risk for total mortality, and show greater longevity of life, even when other lifestyle/demographic factors known to affect longevity are adjusted for in the analysis. A recent analysis is important as it presents data on the relation of alcohol intake to total mortality as well as to specific mortality from cardiovascular disease (CVD) and cancer for a very large number of subjects in the US.