Enzymes NEW US industry forecasts for 2014 & 2019

This comprehensive study analyzes the US market for enzymes, which encompasses both specialty and industrial enzymes typically manufactured using fermentative microorganisms, as well as those sourced from plants and animals. Specific types of enzymes examined include carbohydrases, proteases, polymerases, nucleases, lipases and others. Carbohydrases covered include alpha amylases, glucoamylases, recombinant human glycosidases (rHglycosidases), cellulases, glucose isomerases, lactases and pectinases, among others. Cellulases, as covered in this study, include all enzymes acting on cellulosic fiber-type materials, which encompass both cellulases and hemicellulases. Major enzyme market sectors covered in the study include pharmaceuticals, food and beverage processing, biofuels, research and biotechnology, cleaning products, diagnostics and animal feed. Additionally, several smaller markets are also covered, including biocatalysts, cosmetics and toiletries, pulp and paper, textiles and leather, and others. Dietary supplement/nutraceutical enzyme demand is included in the digestive pharmaceutical market. Pharmaceutical enzyme demand projections are based on existing drugs and developmental compounds presently in clinical trials.

Historical data for 1999, 2004 and 2009 and forecasts for 2014 and 2019 are provided. Unless otherwise indicated, all figures represent demand for enzymes stated in current US dollars. The term “demand” refers to US demand, used interchangeably with the terms sales or apparent consumption, and denotes US production plus imports minus exports. Data are presented at the manufacturers’ level and may also include captive production and use. Tabular details may not add to totals due to independent rounding and ratios may be
rounded for the sake of clarity.

Table of contents

INTRODUCTION

I. EXECUTIVE SUMMARY

II. MARKET ENVIRONMENT
General
Demographic Trends
Macroeconomic Outlook
Consumer Spending
Manufacturing Trends
Food & Beverage Industry Outlook
Agricultural Outlook
Crop Production
Livestock & Poultry
National Health Expenditures
Petroleum & Refining Industry Outlook
Historical Market Trends
Pricing & Product Mix
Environmental & Regulatory Considerations
Intellectual Property Considerations
International Activity
Foreign Trade & US Production
Imports
Exports

III. TECHNOLOGY
General
Enzyme Production Overview
Recombinant DNA Technology
Directed Evolution & Gene Shuffling
Protein Engineering Technology
Molecular Screening & Bioinformatics
Enzyme Immobilization
Extremophilic Enzymes
Enzyme Factories

IV. MARKETS
General
Pharmaceuticals
Pharmaceutical Industry Outlook
Enzyme Demand
Enzyme Replacement Therapy
Neuromodulator
Cosmetic
Noncosmetic
Digestive
Pancreatic Enzymes
Other Digestive Enzymes
Cardiovascular Thrombolytic
Other Pharmaceutical
Pulmonary
All Other
Biofuels
Biofuel Industry Outlook
Enzyme Demand
Starch Enzymes
Cellulosic & Other Biofuel Enzymes
Food & Beverage Processing
Sweeteners
Corn Sweetener Industry Outlook
Enzyme Demand
Dairy Products
Dairy Industry Outlook
Enzyme Demand
Cheese Production
Other Dairy Products
Bakery Products
Baked Goods Industry Outlook
Enzyme Demand
Beverage Processing
Beverage Industry Outlook
Enzyme Demand
Wine & Fruit Juice Production
Beer, Distilled Spirits & Other Beverages
Other Food & Beverage Applications
Research & Biotechnology
Research & Biotechnology Industry Outlook
Enzyme Demand
DNA Amplification & Sequencing
Other Research Enzyme Applications
Cleaning Products
Cleaning Product Industry Outlook
Enzyme Demand
Laundry Detergents
Dishwashing Detergents & Other Cleaners
Diagnostics
Diagnostic Industry Outlook
Enzyme Demand
Animal Feed
Animal Feed Industry Outlook
Enzyme Demand
Non-Starch Polysaccharides
Phytate & Other
Other Enzyme Markets
Biocatalysts
Cosmetics & Toiletries
Textiles & Leather
Textiles
Leather
Pulp & Paper
All Other
Oilfield Recovery & Production
Water Treatment
Odor Control & Decontamination
Waste Treatment
Rubber
Developing Applications

V. PRODUCTS
General
Carbohydrases
Alpha Amylases
Glucoamylases
Recombinant Human Glycosidases
Cellulases
Glucose Isomerases
Lactases
Pectinases
Other Carbohydrases
Proteases
Microbial Proteases
Fibrinolytic Proteases
Rennet/Chymosin
Other Proteases
Polymerases
Nucleases
DNases
Other Nucleases
Lipases
Other Enzymes

VI. INDUSTRY STRUCTURE
General
Market Share
Novozymes
Danisco
Roche
Allergan
Genzyme
Other
Competitive Strategies
Research & Development
Cooperative Agreements
Acquisitions & Divestitures
Manufacturing
Marketing & Distribution
Company Profiles
AB Enzymes, see Associated British Foods
Abbott Laboratories
Agilent Technologies Incorporated
Alere Incorporated 2
Allergan Incorporated
Amano Enzyme Incorporated
Associated British Foods plc
Axcan Intermediate Holdings Incorporated
BASF SE
British Biocell International, see Alere
Cargill Incorporated
Chr. Hansen A/S
Codexis Incorporated
Danisco A/S
DFB Pharmaceuticals Incorporated
Dyadic International Incorporated
Frutarom Limited
Genencor, see Danisco
Genentech, see Roche Holding
Genzyme Corporation
Healthpoint, see DFB Pharmaceuticals
Iogen Corporation
Ipsen
Johnson & Johnson
Life Technologies Corporation
Lonza Group Limited
Microbix Biosystems Incorporated
MP Biomedicals LLC
National Enzyme Company
New England BioLabs Incorporated
Novozymes A/S
Promega Corporation
Roche Holding Limited
Royal DSM NV
Shire plc
Solstice Neurosciences Incorporated
Solvay SA
Specialty Enzymes & Biotechnologies Company
Verenium Corporation
Other Companies Mentioned in Study

LIST OF TABLES

SECTION I -- EXECUTIVE SUMMARY
Summary Table

SECTION II -- MARKET ENVIRONMENT
1 Population & Households
2 Macroeconomic Indicators
3 Personal Consumption Expenditures
4 Manufacturers’ Shipments
5 Food & Beverage Shipments
6 Agricultural Indicators
7 Major Crop Production
8 Livestock & Poultry Population
9 National Health Expenditures
10 Petroleum Industry Indicators
11 Enzyme Market, 1999-2009
12 Selected Enzyme Pricing
13 Enzyme Production & Foreign Trade

SECTION IV -- MARKETS
1 Enzyme Demand by Market
2 Pharmaceutical Shipments
3 Pharmaceutical Enzyme Demand by Market, Status & Product
4 Enzyme Replacement Therapy Demand by Pharmaceutical & Product
5 Neuromodulator Enzyme Demand
6 Digestive Enzyme Demand by Application & Product
7 Cardiovascular Thrombolytic Enzyme Demand by Application, Type & Product
8 Other Pharmaceutical Enzyme Demand by Type & Product
9 Biofuel Supply & Demand
10 Biofuel Enzyme Demand by Application & Product
11 Food & Beverage Enzyme Demand by Application & Product
12 Corn Sweetener Supply & Demand
13 Corn Sweetener Enzyme Demand by Application & Product
14 Dairy Product Shipments
15 Dairy Enzyme Demand by Application & Product
16 Cheese Enzyme Demand
17 Other Dairy Product Enzyme Demand
18 Bakery Product Shipments
19 Bakery Product Enzyme Demand
20 Beverage Shipments
21 Beverage Enzyme Demand
22 Other Food & Beverage Enzyme Demand
23 Research Expenditures
24 Research & Biotechnology Enzyme Demand by Type & Product
25 DNA Amplification & Sequencing Enzyme Demand
26 Other Research & Biotechnology Enzyme Demand
27 Cleaning Product Supply & Demand
28 Cleaning Product Enzyme Demand by Application & Product
29 Laundry Detergent Enzyme Demand
30 Dishwashing & Other Cleaning Product Enzyme Demand
31 In Vitro Diagnostic Product Shipments
32 Diagnostic Enzyme Demand
33 Animal Feed Shipments
34 Animal Feed Enzyme Demand by Application & Product
35 Other Enzyme Demand by Market & Product
36 Biocatalyst Enzyme Demand
37 Cosmetic & Toiletry Enzyme Demand
38 Textile & Leather Enzyme Demand by Application & Product
39 Pulp & Paper Enzyme Demand
40 All Other Enzyme Markets

SECTION V -- PRODUCTS
1 Enzyme Demand by Product
2 Carbohydrase Demand by Product & Market
3 Alpha Amylase Demand
4 Glucoamylase Demand
5 Recombinant Human Glycosidase Demand
6 Cellulase Demand
7 Glucose Isomerase Demand
8 Lactase Demand
9 Pectinase Demand
10 Other Carbohydrase Demand
11 Protease Demand by Product & Market
12 Microbial Protease Demand
13 Fibrinolytic Protease Demand
14 Rennet/Chymosin Demand
15 Other Protease Demand
16 Polymerase Demand
17 Nuclease Demand by Product & Market
18 DNase Demand
19 Other Nuclease Demand
20 Lipase Demand
21 Other Enzyme Demand

SECTION VI -- INDUSTRY STRUCTURE
1 Enzyme Sales by Company, 2009
2 Selected Cooperative Agreements
3 Selected Acquisitions & Divestitures

LIST OF CHARTS

SECTION II -- MARKET ENVIRONMENT
1 Enzyme Market, 1999-2009
2 US Enzyme Imports by Source, 2009
3 US Enzyme Exports by Destination, 2009

SECTION IV -- MARKETS
1 Enzyme Demand by Market, 2009

SECTION V -- PRODUCTS
1 Enzyme Demand by Product, 2009

SECTION VI -- INDUSTRY STRUCTURE
1 US Enzyme Market Share by Company, 2009

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By market: United States (in North America)