Critiques from the International Scientific Forum on Alcohol Research
By: International Scientific Forum on Alcohol Research
The International Scientific Forum on Alcohol Research hosts forums that look at research conducted around the world on the relationship between alcohol consumption and health.
Three major papers on the association of alcohol consumption and cancer have recently been published. ISFAR forum members considered that all were well-done, and presented valuable new information on the topic.
Among elderly people, falls leading to hip fracture are a major health problem, leading to severe morbidity and mortality. Underlying factors that increase the risk of hip and other fractures include osteoporosis and low bone mineral density, as well as an unsteady gait making falls more common.
Among people who consume alcohol, it would be assumed that the excess calories provided by the alcohol would add to their risk of obesity. However, current data suggests that the association may be more complex.
Mediterranean area. The primary basis of the diet is on plant-based foods (whole grains, vegetables, fruits), olive oil, moderate wine consumption, and limited intake of meat or dairy products.
Last month, the 2015 Dietary Guidelines Advisory Committee submitted the 'Scientific Report of the 2015 Dietary Guidelines Advisory Committee' to the Secretaries of the US Department of Health & Human Services (HHS) and the US Department of Agriculture (USDA).
The authors of a recent paper on alcohol and mortality, and the case for age-specific alcohol consumption guidelines published in the BMJ, have carried out a regression analysis to examine the association of reported alcohol consumption with all-cause mortality, dividing their sample into different age groups.
A recent paper, from a group of experienced investigators in Denmark using data from a large population-based cohort, attempted to judge how drinking pattern affects the risk of a subject developing alcoholic cirrhosis.
An analysis of data from 'Atherosclerosis Risk in Communities (ARIC)' evaluated the effects of alcohol consumption at baseline, and the cumulative average intake based on several later assessments during a 24-year follow-up period, on the risk of the development of heart failure (HF).
A number of prospective studies have shown that moderate drinkers are at lower risk of developing dementia or cognitive impairment than abstainers or heavy drinkers.
A recent case-control study compared the risk of having a high level of haemoglobin A1c, a measure of hyperglycemia, and of the waist/height ratio, a measure of obesity, according to reported alcohol consumption.
It has long been known that genetic and other environmental factors modify the association between alcohol consumption and a variety of diseases, especially coronary heart disease (CHD).
Excessive maternal alcohol consumption during pregnancy (especially among women with alcohol dependency) is known to markedly increase the risk of the foetus showing a group of developmental disorders defined as foetal alcohol spectrum syndrome (FASD), with the most serious form being foetal alcohol syndrome (FAS).
A recent meta-analysis was produced by authors who, in the past, have tended to argue that the demonstrated inverse association between moderate alcohol consumption and ischemic heart disease (IHD) shown in most studies is due to confounding by other lifestyle factors.
Hepatic cirrhosis frequently precedes the development of liver cancer, and excessive alcohol consumption is known to be one cause of cirrhosis.
The study concerned is based on a large number of women participating in a clinical trial (enhanced screening for certain cancers versus routine care) focusing on prostate, lung, colorectal, and ovarian cancer.
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