Critiques from the International Scientific Forum on Alcohol Research
By: International Scientific Forum on Alcohol Research
The International Scientific Forum on Alcohol Research hosts forums that look at research conducted around the world on the relationship between alcohol consumption and health.
A recent paper, which uses a very large dataset from subjects of European descent, uses a Mendelian randomisation analysis to estimate the effects of alcohol consumption on cardiovascular disease (CVD), using as the instrumental variable an uncommon allele affecting alcohol metabolism, the ADH1B rs1229984 variant.
The large European Prospective Investigation into Cancer and Nutrition Study (EPIC) has released a new analysis of the relation of alcohol consumption to mortality.
The Interheart Study is a large international collaborative project which follows individuals with a first heart attack (myocardial infarction) and compares their age- and sex-matched controls across 52 countries in Asia, Europe, the Middle East, Africa, Australia, North and South America.
An inverse or reduced risk association between moderate alcohol consumption and total mortality has been reported in most prospective epidemiologic studies, even after adjustments for all known potential confounders such as educational level, job and health.
Epidemiologists are often faced with reported adverse health effects of alcohol among subjects reporting very low levels of consumption, levels that physiologically should not cause diseases such as cancer.
A paper by Blomster JI, to be published in Diabetes Care is based on the largest study on diabetes in the world.
A recent study of late-life alcohol consumption and drinking problems was based on a sample of “late-middle-aged” (55–65 years old at baseline) “community residents” who were recruited from the western part of the US.
Previous research has shown that alcohol consumption may be associated with a reduced risk of rheumatoid arthritis, lupus erythematosus, and other autoimmune diseases. There have also been reports that alcohol may lower the risk of multiple sclerosis (MS).
A large group of investigators participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study have reported on the association of alcohol consumption with disease-specific mortality over a 12-year period among a very large number of men and women.
A new meta-analysis has been conducted to assess the effects of alcohol consumption on the risk of gout.
A recent report from more than 59,000 women in the Women’s Health Initiative related alcohol consumption to the risk of melanoma (MM) and non-melanoma skin cancer (NMSC).
Alcohol is known to be a risk factor for breast cancer in Caucasian women, but the evidence in African-American (AA) women is limited and results from previous studies are inconclusive.
In an attempt to judge the harmful and beneficial health effects related to alcohol consumption, scientists in Denmark have carried out analyses comparing alcohol-attributable and alcohol-preventable mortality in the country.
Moderate alcohol intake, compared with abstinence, has been related to lower inflammatory markers and a reduced risk of many auto-immune diseases, including rheumatoid arthritis (RA), systemic lupus erythematosus, autoimmure diabetes, and Graves hyperthyroidism.
Many epidemiologic studies have shown a slight increase in the risk of breast cancer and colorectal cancer to be associated with alcohol consumption.
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