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International Scientific Forum on Alcohol Research
Columns by International Scientific Forum on Alcohol Research
The International Scientific Forum on Alcohol Research hosts forums that look at research conducted around the world on the relationship between alcohol consumption and health.
Articles by International Scientific Forum on Alcohol Research
Hepatic cirrhosis frequently precedes the development of liver cancer, and excessive alcohol consumption is known to be one cause of cirrhosis.
The study concerned is based on a large number of women participating in a clinical trial (enhanced screening for certain cancers versus routine care) focusing on prostate, lung, colorectal, and ovarian cancer.
The large majority of prospective epidemiologic studies on the effects of alcohol consumption and the risk of coronary heart disease and stroke have shown a significant reduction in risk for moderate drinkers.
While numerous prospective epidemiologic studies have provided evidence that light-to-moderate amounts of alcohol reduce the risk of dementia and heavy drinking increases the risk, there are few studies on the effects of alcohol on brain structure assessed by magnetic resonance imaging (MRI).
In a new analysis from the Nurses’ Health Study, investigators have related repeatedly-assessed long-term alcohol intake, and related the cumulative average intake over time to the risk of invasive uterine cancer.
A recent paper, which uses a very large dataset from subjects of European descent, uses a Mendelian randomisation analysis to estimate the effects of alcohol consumption on cardiovascular disease (CVD), using as the instrumental variable an uncommon allele affecting alcohol metabolism, the ADH1B rs1229984 variant.
The large European Prospective Investigation into Cancer and Nutrition Study (EPIC) has released a new analysis of the relation of alcohol consumption to mortality.
The Interheart Study is a large international collaborative project which follows individuals with a first heart attack (myocardial infarction) and compares their age- and sex-matched controls across 52 countries in Asia, Europe, the Middle East, Africa, Australia, North and South America.
Most epidemiologic studies have shown a reduction in the risk of ischemic stroke (and total stroke, as ischemic stroke is by far the most common type in western countries) to be associated with light to moderate alcohol consumption.
An inverse or reduced risk association between moderate alcohol consumption and total mortality has been reported in most prospective epidemiologic studies, even after adjustments for all known potential confounders such as educational level, job and health.
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